IRF7 antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Recommended dilution range for Western blot analysis is 1:1,000~ 2,000. Recommended starting dilution is 1:1,000.
IRF7 belongs to the interferon regulatory transcription factor (IRF) family. IRF7 plays a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue.
[1] Taniguchi, T. et al. (2001) Annu Rev Immunol 19, 623-55.
[2] Honda, K. and Taniguchi, T. (2006) Nat Rev Immunol 6, 644-58.
[3] Au, W.C. et al. (1998) J Biol Chem 273, 29210-7.
[4] Wathelet, M.G. et al. (1998) Mol Cell 1, 507-18.
[5] Marié, I. et al. (1998) EMBO J 17, 6660-9.
[6] Sato, M. et al. (2000) Immunity 13, 539-548.
[7] Honda, K. et al. (2005) Nature 434, 772-7.
[8] Colina, R. et al. (2008) Nature 452, 323-8.
[9] Lin, R. et al. (2000) J Biol Chem 275, 34320-7.
[10] Yang, H. et al. (2003) J Biol Chem 278, 15495-504.
