[1] Zhang Z, et al. Discovery of piperazin-1-ylpyridazine-based potent and selective stearoyl-CoA desaturase-1 inhibitors for the treatment of obesity and metabolic syndrome. J Med Chem. 2013 Jan 24;56(2):568-83. DOI:
10.1021/jm301661h[2] Meingassner JG, et al. Pharmacological inhibition of stearoyl CoA desaturase in the skin induces atrophy of the sebaceous glands. DOI:
10.1038/jid.2013.89