Neostigmine Iodide is a parasympathomimetic compound that acts as a reversible acetylcholinesterase inhibitor. It is used to improve muscle tone in people with myasthenia gravis and routinely in anesthesia to reverse the effects of non-depolarizing muscle relaxants such as rocuronium and vecuronium at the end of an operation, usually in a dose of 25 to 50 μg per kilogram. It can also be used for urinary retention resulting from general anesthesia and to treat curariform drug toxicity.
