DSPE-PEG-PDP, MW 2,000 is a linear polyPEG containing a DSPE lipid group and PDP. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The PDP group selectively reacts with thiol, sulfhydryl or mercapto to form a disulfide bond.
DSPE-PEG(2000) PDP has been used in the preparation of targeted liposomes. It has also been used as a PEGylated lipid for antibody conjugation to vesicles.
DSPE-PEG(2000) PDP is a functionalized polyethylene glycol (PEG) conjugated lipid.
DSPE-PEG(2000) PDP serves as a precursor of DSPE-PEG2000-SH.
![1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[PDP(polyethylene glycol)-2000] (aMMoniuM salt) Structure](/CAS/20240320/GIF/474922-24-2.gif)