As a starting material to prepare rod-like hydrogen-bonded organic frameworks through Stille-coupling using 2,5-bis(trimethyltin)heterocycle, Pd(PPh3)4, and CuI.
As a substrate in the C-H arylation reaction of pyroglutamic acid derivatives with aryl and heteroaryl iodides; catalyzed by the palladium catalyst.
As a substrate in the synthesis of trifluoroborates, which are further converted to protected boronic acids.
As a starting material in the synthesis of amino acid MIDA boronates as new building blocks by reacting with protected iodoalanine.