KP-6, a polypeptide, is a Wnt/β-catenin signal inhibitor. KP-6 inhibits TGF-β and blocks rush fibrosis signal path crucial in vivo. KP-6 suppresses Renal tissues damage and renal fibrosis, and reverse the course of disease of chronic kidney disease (CKD)[1].
References
[1] Youhua Liu, et al. Purposes of the micromolecule polypeptide KP 6 in the medicine for preparing treatment CKD. CN106822865A.