Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice . Goat Anti-Mouse IgG (γ-chain specific)-Biotin antibody specific for mouse IgG when tested against mouse IgA, IgG (all subclasses), and IgM.