Hexanoyl Coenzyme A (sodium salt)

Hexanoyl-coenzyme A (CoA) is a medium-chain fatty acyl CoA. It is the preferred acyl donor substrate for ghrelin O-acyltransferase (GOAT) over octanoyl-CoA (Item No. 27868) in enzyme assays.1 It is a precursor in the biosynthesis of olivetolic acid, a resorcinolic acid precursor in the synthesis of certain phytocannabinoids.2WARNING This product is not for human or veterinary use.

[1] HIDEKO OHGUSU. Ghrelin O-acyltransferase (GOAT) has a preference for n-hexanoyl-CoA over n-octanoyl-CoA as an acyl donor[J]. Biochemical and biophysical research communications, 2009, 386 1: Pages 153-158. DOI: 10.1016/j.bbrc.2009.06.001
[2] FUTOSHI TAURA. Characterization of olivetol synthase, a polyketide synthase putatively involved in cannabinoid biosynthetic pathway[J]. FEBS Letters, 2009, 583 12: Pages 2061-2066. DOI: 10.1016/j.febslet.2009.05.024