NH-bis(PEG4-Boc) is a Boc protected PEG reagent whiich is reactive with carboxylic acids, activated NHS esters,. Boc group can be removed under acidic conditions.
Uses
NH-bis(PEG4-C2-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
