Cholesteryl Palmitate-d9

Cholesteryl palmitate-d9 is intended for use as an internal standard for the quantification of cholesteryl palmitate (Item No. 26473) by GC- or LC-MS. Cholesteryl palmitate is a cholesterol ester. It is a major cholesterol ester found in human meibum and has been used to form a stable tear film to study amphiphilic block copolymers as surfactants for dry eyes.1 Cholesteryl palmitate levels in amniotic fluid are decreased in pregnancies in which infants later developed respiratory distress syndrome and in patients with well-controlled diabetes.2,3 Levels of cholesteryl palmitate are increased in bronchoalveolar lavage fluid (BALF) from patients with chronic interstitial pneumonia.4WARNING This product is not for human or veterinary use.

[1] WARD E SHINE  James P M. Polar lipids in human meibomian gland secretions.[J]. Current Eye Research, 2003, 26 2: 89-94. DOI: 10.1076/ceyr.26.2.89.14515
[2] JACK LUDMIR M.D. Cholesteryl palmitate as a predictor of fetal lung maturity[J]. American journal of obstetrics and gynecology, 1987, 157 1: Pages 84-88. DOI: 10.1016/s0002-9378(87)80351-4
[3] J LUDMIR. Amniotic fluid cholesteryl palmitate in pregnancies complicated by diabetes mellitus.[J]. Obstetrics and gynecology, 1988, 72 3 Pt 1: 360-362.
[4] NAOKO FUKUHARA . Cholesteryl palmitate crystals in bronchoalveolar lavage fluid smears as a possible prognostic biomarker for chronic interstitial pneumonia: A preliminary study[J]. Respiratory investigation, 2016, 54 2: Pages 109-115. DOI: 10.1016/j.resinv.2015.09.003