BDP fl-PEG4-(4E)-TCO

BDP FL-PEG4-TCO is a BDP FL linker containing a TCO group and a hydrophilic PEG spacer arm. The TCO group allows site-specific conjugation by Click Chemistry and is ideal for conjugation with of antibodies, proteins or probes. The hydrophilic PEG spacer arm can increase water solubility.

BDP FL-PEG4-TCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PEGs

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005