5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester

5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester is an inhibitor of G protein-coupled receptor kinase 2. 5-[2-(5-Nitro-2-furanyl)ethenyl]-2-furancarboxylic Acid Methyl Ester was shown to normalize vascular endothelial function in type 2 diabetic mice by improving β-arrestin 2 translocation and ameliorating Akt/eNOS signal dysfunction.

Cell permeable: no', 'Primary Target
βARK1 (β-Adrenergic Receptor Kinase 1)', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 126 μM against βARK1 (β-Adrenergic Receptor Kinase 1)