Hibiscus syriacus was widely found in eastern and southern Asia, and it is an ornamentalshrub. The plant is cultivated for decorative purposes because its flower isthe national flower of Korea. Extracts of several parts of H. syriacus have been usedas a prescription and effective alternative medicine in Asia (Yoon et al. 2017). Hsuet al. (2015) reported that H. syriacus skin extracts (HSSE) of 15 varieties werescreened, including seven crude extracts and eight pure compounds. After treatingestrogen receptor (ER)-negative and TNBC cell line (MDA-MB-231) with theextracts, functional assays were performed, which showed cell viability-inhibitoryeffects.
