13C6-4-Nitrophenylhydrazine (hydrochloride)

13C6-4-Nitrophenylhydrazine is intended for use as an internal standard for the quantification of 4-nitrophenylhydrazine by GC- or LC-MS. 13C6-4-Nitrophenylhydrazine is a byproduct in the synthesis of 13C6-3-nitrophenylhydrazine (Item No. 20744). 4-Nitrophenylhydrazine has been used as an intermediate in the synthesis of benzo-indazole derivatives with anti-uterotrophic activity in vivo and pyrazolobenzothiazine derivatives with antiviral activity in vitro.1,2WARNING This product is not for human or veterinary use.

[1] MAHMOUD A. RAGAB . Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity[J]. Bioorganic Chemistry, 2022, 119: Article 105554. DOI: 10.1016/j.bioorg.2021.105554
[2] MARIA LETIZIA BARRECA*. Structure-Based Discovery of Pyrazolobenzothiazine Derivatives As Inhibitors of Hepatitis C Virus Replication[J]. Journal of Medicinal Chemistry, 2013, 56 6: 2270-2282. DOI: 10.1021/jm301643a