It is one of a series of AMPA modulators
matergic AMPA receptors.
in vivo
CX614 (1 or 10 mg/kg, i.p., twice a day) significantly increases BDNF mRNA in hippocampus and cortex of P5 mice, confirming upregulation of hippocampal BDNF mRNA levels by positive allosteric modulators of AMPA receptors[2].
