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依特柳酯

依特柳酯

中文名称:依特柳酯
英文名称:etersalate
CAS号:62992-61-4
分子式:C19H19NO6
分子量:357.36
EINECS号:2637803
Mol文件:62992-61-4.mol
依特柳酯 结构式

依特柳酯 性质

熔点 139-141°
沸点 561.8±40.0 °C(Predicted)
密度 1.263±0.06 g/cm3(Predicted)
储存条件 Store at -20°C
溶解度 溶于二甲基亚砜
酸度系数(pKa) 14.49±0.70(Predicted)

依特柳酯 用途与合成方法

Eartsalate 抑制血小板功能并降低血栓素 A2 (TXA2) 水平。

TXA 2

Ex vivo antiplatelet properties of Etersalate and its effects on serum thromboxane A2 (TXA2) levels and prostaglandin I2 (PGI2) generation are studied in human volunteers at two levels of oral dosing. Etersalate inhibits at the lower dosage platelet function and decreased TXA2 levels, but PGI2 generation from rat aortic rings is stimulated when incubated with plasma from Etersalate-treated donors. Blood coagulation parameters remain within normal values. Etersalate administration can act on platelet arachidonate metabolism at a different level than that of the cyclooxygenase pathway.

安全信息

毒性LD10 orally in rats: 7000 mg/kg (Leterier, Grafulia, 1977)

依特柳酯供应商 更多

TargetMol中国(陶术生物)
联系电话: 4008200310
产品介绍:
中文名称:化合物 T15252
英文名称:Etersalate;Etersalate
CAS:62992-61-4
纯度:98%
包装信息:5 mg

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