倍氯米松
中文名称:倍氯米松
英文名称:NEP
CAS号:2414276-32-5
分子式:C29H31AsN4O5S2
分子量:654.63
EINECS号:
Mol文件:2414276-32-5.mol
倍氯米松 用途与合成方法
NEP (VDP-green (NEP)) 是一种基于分子内电荷转移 (ICT) 机制的感应荧光探针，用于感应含邻二硫醇的蛋白质 (VDPs)。NEP 在活细胞和动物体内对 VDPs 表现出高选择性，并显示强绿色荧光信号 (λex/λem=430/535 nm)。NEP 具有用于帕金森氏症研究的潜力。
NEP (1-30 μM; 6 hours) has no or little cytotoxicity in HepG2 and PC12 cells.
NEP (10 μM; 4 hours) causes the fluorescence intensity to decrease gradually in PC12 cells pretreated with 6-OHDA (0, 50, 100, and 200 μM; for 30 min).
NEP contains a dithiarsolane moiety (five-membered As-S ring) as the receptor of VDPs. In the presence of VDPs, NEP displays a strong green fluorescence signal produced by the cyclic dithiarsolane cleavage and subsequent intramolecular cyclization to liberate the fluorophore. NEP maintains a reliable fluorescence response within the range of pH 7-10.
NEP (10 μM; for 4 h) causes the obvious green signal in zebrafishes (4 day old).
倍氯米松供应商 更多
TargetMol中国（陶术生物）
联系电话：021-021-33632979 15002134094
产品介绍：
中文名称：BecloMethasone;BecloMethasone;Beclometasone;倍氯米松
英文名称：NEP
CAS：2414276-32-5
包装信息：10 mg;5 mg
备注： 90+%，具体纯度信息请见官网
