4-Methylethcathinone metabolite (hydrochloride) ((±)-Pseudoephedrine stereochemistry)

4-methylethcathinone (4-MEC) (hydrochloride) (Item No. 9001069) is a cathinone derivative identified in several designer, recreational drugs that are sold as “legal high” replacements for controlled stimulants such as methamphetamine and 3,4-methylenedioxymethamphetamine.1,2,3 This metabolite of 4-MEC features conversion of the β-keto group to β-hydroxy and is an enantiomeric mixture of the R,R and S,S orientations at carbons one and two, as in pseudoephedrine. The physiological and toxicological properties of this compound have not been elucidated. This product is intended for research and forensic applications.WARNING This product is not for human or veterinary use.

[1] FABRIZIO SCHIFANO. Mephedrone (4-methylmethcathinone; ’meow meow’): chemical, pharmacological and clinical issues.[J]. Psychopharmacology, 2011, 214 3: 593-602. DOI: 10.1007/s00213-010-2070-x
[2] EMAN Y. SANTALI . Synthesis, full chemical characterisation and development of validated methods for the quantification of (±)-4′-methylmethcathinone (mephedrone): A new “legal high”[J]. Journal of pharmaceutical and biomedical analysis, 2011, 56 2: Pages 246-255. DOI: 10.1016/j.jpba.2011.05.022
[3] SIMON GIBBONS  Mire Z. An analysis of the ‘legal high’ mephedrone[J]. Bioorganic & Medicinal Chemistry Letters, 2010, 20 14: Pages 4135-4139. DOI: 10.1016/j.bmcl.2010.05.065