Tetradecanoic-2,2-d2 acid

Myristic acid-d₂ is intended for use as an internal standard for the quantification of myristic acid by GC- or LC-MS. Myristic acid is a 14-carbon saturated fatty acid. It is incorporated into myristoyl coenzyme A (myristoyl-CoA) and transferred by N-myristoyltransferase to the N-terminal glycine of certain proteins either during translation to modify protein activity or post-translationally in apoptotic cells.

Tetradecanoic-2,2-d2 Acid (CAS# 30719-21-2) is a useful isotopically labeled research compound.

[1] GUO-QIANG ZHENG. Synthesis of myristoyl CoA analogues and myristoyl peptides as inhibitors of myristoyl CoA: Protein N-myristoyltransferase[J]. Journal of pharmaceutical sciences, 1994, 83 2: 233-238. DOI: 10.1002/jps.2600830224
[2] DALE D.O. MARTIN  Luc G B  Erwan Beauchamp. Post-translational myristoylation: Fat matters in cellular life and death[J]. Biochimie, 2011, 93 1: Pages 18-31. DOI: 10.1016/j.biochi.2010.10.018