Ac-LEHD-CHO is an inhibitor for caspase 8/9. Ac-LEHD-CHO prevents GalN/TNF-α-induced hepatotoxicity and hepatocyte apoptosis[1].
References
[1] Kermer P, et al., Caspase-9: involvement in secondary death of axotomized rat retinal ganglion cells in vivo. Brain Res Mol Brain Res. 2000 Dec 28;85(1-2):144-50. DOI:10.1016/s0169-328x(00)00256-4