N-Tosyl-S-difluoromethyl-S-phenyl
sulfoximine is a novel and efficient difluoromethylation reagent for transferring the CF2H group to S-, N-, and
C-nucleophiles under water-free conditions[1].
Reactions
(1) Difluromethylation of S-, N-, and C-nucleophiles.
References
[1] WEI ZHANG; Jinbo H; Fei Wang. N-Tosyl-S-difluoromethyl-S-phenylsulfoximine: A New Difluoromethylation Reagent for S-, N-, and C-Nucleophiles[J]. Organic Letters, 2009. DOI:10.1021/ol900567c.
![Benzenesulfonamide, N-[(difluoromethyl)oxidophenyl-λ4-sulfanylidene]-4-methyl- Structure](/CAS/20211123/GIF/1097192-99-8.gif)
![Benzenesulfonamide, N-[(difluoromethyl)oxidophenyl-λ4-sulfanylidene]-4-methyl-](/NewsImg/2024-01-23/6384160548901623448245000.png "Benzenesulfonamide, N-[(difluoromethyl)oxidophenyl-λ4-sulfanylidene]-4-methyl-")