This isomeric alkaloid from the leaf extract of Erythroxylon truxillense Rusby
sinters at 45°C and decomposes above 120°C. It is laevorotatory with [α]D -
29.3°. On acid hydrolysis it yields MeOH, (-)-ecgonine and {3-truxillic acid, m.p.
206°C and may be synthesized in a similar manner to the preceding base.
β-Truxilline is an alkaloid found in coca leaves. It is an impurity of illicit Cocaine (C633500), which inhibits the dopamine, norepinephrine, and serotonin transporters.
Hesse., Pharm. Zeit., 407,668 (1887)
Liebermann., Ber., 21,2342 (1888)
Hesse., ibid, 22,665 (1889)
Liebermann, Drory., ibid, 22,682 (1889)