MMP Inhibitor I (trifluoroacetate salt)

MMP inhibitor I is a peptide inhibitor of matrix metalloproteinase-1 (MMP-1), MMP-2, and MMP-3 (IC₅₀s = 1.3, 30, and 150 μM, respectively). It is selective for MMP-1, MMP-2, and MMP-3 over the proteases thermolysin, urease, trypsin, α-chymotrypsin, plasmin, and elastase at concentrations up to 4 mM.

[1] ODAKE S. Inhibition of Matrix Metalloproteinases by Peptidyl Hydroxamic Acids[J]. Biochemical and biophysical research communications, 1994, 199 3: Pages 1442-1446. DOI: 10.1006/bbrc.1994.1392