C19 Ceramide is a naturally occurring ceramide that has been found in
J. juncea extracts as well as rat brain and mouse heart.
1,2,3 It is elevated in adult and decreased in juvenile whole rat brain extracts by 114 and 37%, respectively, following chronic ethanol exposure.
2 C19 Ceramide is also increased in mouse hearts following administration of angiotensin II .
3
1. Krishna, N., Muralidhar, P., Kumar, M.M., et al. A new sphingolipid from the gorgonian Junceella juncea of the Indian ocean Nat. Prod. Res. 18(6),551-555(2004).
2. Roux, A., Muller, L., Jackson, S.N., et al. Chronic ethanol consumption profoundly alters regional brain ceramide and sphingomyelin content in rodents ACS Chem Neurosci. 6(2),247-259(2015).
3. Glenn, D.J., Cardema, M.C., Ni, W., et al. Cardiac steatosis potentiates angiotensin II effects in the heart Am. J. Physiol. Heart Circ. Physiol. 308(4),H339-350(2015).
