Tadalafil Impuirty 13

(1R,?3R)?-1-?(1,?3-?Benzodioxol-?5-?yl)?-?2,?3,?4,?9-?tetrahydro-1H-?pyrido[3,?4-?b]?indole-?3-?carboxamide is an analogue of Tadalafil (T004500), which is a human PDE5 inhibitor. (1R,?3R)?-1-?(1,?3-?Benzodioxol-?5-?yl)?-?2,?3,?4,?9-?tetrahydro-1H-?pyrido[3,?4-?b]?indole-?3-?carboxamide is a weak inhibitor of TbrPDEB1.