4-(4-(prop-2-ynyloxy)benzoyl)benzoic acid

4-[4-(2-Propyn-1-yloxy)benzoyl]benzoic Acid, is a benzophenone residue used for Protein Photolabeling. It can also be used for the synthesis of new Thiodigalactoside-Based chemical probes to label galectin-3.

4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

reaction type: click chemistry
reagent type: cross-linking reagent