Pristinamycin is a systemic antibiotic of the synergistins/
streptogramins class, composed of two subunits: pristinamycin
IA and pristinamycin IIA. It induces several
types of drug reactions such as maculo-papular exanthema,
systemic dermatitis, or acute generalized exanthematous
pustulosis. Some patients have been previously
skin-sensitized by virginiamycin. Crossreactivity
is expected to virginiamycin and to the associated dalfopristin
and quinupristin.
