2-(Dimethylamino)-N-[11-hydroxy-3-isopropyl-5,8-dioxo-7-benzyl-2-oxa-6,9-diazabicyclo[10.2.2]hexadeca-12,14(1),15-trien-4-yl]-3-methylpentanamide

An alkaloid of the peptide class, this base if found in Panda oleosa Pierre. It is best crystallized from AcOEt when it yields clusters of colourless crystals. It has [α]_D - 103° (c 0.5, CHCI3) and gives a laevorotatory hydrochloride, m.p. 235°C (dec.); [α]_D - 77° (c 1.0, MeOH). The presence of a hydroxyl group is shown by the formation of the O-acetate, m.p. 30S-7°C; [α]_D - 98° (c 0.5, pyridine), giving a hydrochloride, m.p. 280°C (dec.); [α]_D - 89° (c 1.0, MeOH). Three of the nitrogen atoms are present as amide groups, the fourth being a dimethylamino group.

Pandamine is a natural alkaloid that can be extracted from Panda oleosa[1].

ChEBI: Pandamine is a cyclic peptide.

Pais et al., Bull. Soc. Chim. Fr., 817 (1964)