Anti-GAS3, Anti-Growth arrest-specific 3, Anti-Peripheral myelin protein 22

Anti-PMP22 antibody produced in rabbit has been used in:

• immunofluorescence
• western blotting
• immunohistochemistry

PMP22 (peripheral myelin protein-22) is a tetraspan integral membrane protein, that contains four putative transmembrane domains. It is expressed in the peripheral nervous system. PMP22 is produced by myelinating Schwann cells. It is an important constituent of peripheral myelin. This gene is mapped to human chromosome 17p11.2.

PMP22 (peripheral myelin protein-22) participates in the progression of CNS (central nervous system) myelin. It modulates self-renewal and chemoresistance of gastric cancer cells. Mutation in PMP22 results in Charcot-Marie tooth disease.