Monoclonal Anti-TBP antibody produced in mouse has been used in:
immunoblotting
co-immunoprecipitation
immunohistochemistry
General Description
TBP (TATA-binding protein) is encoded by the gene mapped to human chromosome 6q27. The encoded protein is a key constituent of RNA polymerase II transcription apparatus in eukaryotic cells.
Biochem/physiol Actions
TBP facilitates promoter recognition with the help of the sequence-specific binding of the TATA element found in many promoters.