N-Piperidinyl Etonitazene (citrate)

N-Piperidinyl etonitazene (citrate) (Item No. 33168) is an analytical reference standard categorized as an opioid.1 N-Piperidinyl etonitazene induces antinociceptive effects in mice in the hot plate test. N-Piperidinyl etonitazene is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.WARNING This product is not for human or veterinary use.

[1] MARTHE M. VANDEPUTTE. First identification, chemical analysis and pharmacological characterization of N-piperidinyl etonitazene (etonitazepipne), a recent addition to the 2-benzylbenzimidazole opioid subclass[J]. Archives of Toxicology, 2022, 96 6: 1865-1880. DOI: 10.1007/s00204-022-03294-2
[2] LAURA B KOZELL. Pharmacologic Characterization of Substituted Nitazenes at μ, κ, and Δ Opioid Receptors Suggests High Potential for Toxicity.[J]. Journal of Pharmacology and Experimental Therapeutics, 2024: 219-228. DOI: 10.1124/jpet.123.002052
[3] MENG-HUA M. TSAI, LEI SHI*   In Vitro Functional Profiling of Fentanyl and Nitazene Analogs at the μ-Opioid Receptor Reveals High Efficacy for Gi Protein Signaling[J]. ACS Chemical Neuroscience, 2024, 15 4: 854-867. DOI: 10.1021/acschemneuro.3c00750