IMCTA-C14 is a detergent and derivative of the microbial metabolite 4-trehalosamine (Item No. 40229).1 It has a critical micelle concentration (CMC) of 0.11 mM and a hydrophilic-lipophilic balance (HLB) value of 9.72. IMCTA-C14 (0.05 and 0.5%) extracts proteins, including membrane proteins, from OVK18 ovarian cancer cells. It is active against several strains of various bacteria (MICs = 8-128 µg/ml) and is cytotoxic against a panel of 52 cancer cell lines (IC50s = 2.9-29.2 µg/ml). IMCTA-C14 (50 µM) induces autophagy in OVK18 cells.WARNING This product is not for human or veterinary use.
