3,4-Dichlorobicyclo[3.2.1]oct-2-ene is an intermediate in the synthesis of 3-Bicyclo[3.2.1]octanone (B382840), a reactant used in the synthesis of polycyclic acid derivatives as selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1).