This trans-stilbene derivative (FW = 212.25 g/mol; CAS 102-61-4; M.P. =
155.5-156°C; low solubility in water), also known as (E) -3,5-stilbenediol
and trans-3,5-dihydroxystilbene and named systematically as 5-[ (E) -2-
phenylethenyl]benzene-1,3-diol, occurs naturally in the hardwood of pine
and other woody plants. Pinosylvin exxhibits micromolar Ki values for
specific isozymes of stilbene synthase and chalcone synthase.
Target (s) : chalcone synthase; stilbene synthase; tyrosinase, or
monophenol monooxygenase.
