Dibutyl 3-
hydroxybutyl phosphate (TBP-
OH; ) is a compound produced from the metabolism of the organophosphorus solvent, tributyl phosphate (TBP). Incubation of goldfish liver microsomes in the presence of NADPH has been shown to convert TBP into TBP-
OH and dibutyl phosphate.
1 TBP-
OH has also been produced during radiolysis of TBP.
2 (S)-
TBP-
OH is an optically active isomer of TBP-
OH.
1. Sasaki, K., Suzuki, T., Takeda, M., et al. Metabolism of phosphoric acid triesters by goldfish, Carassius auratus Eisei Kagaku 31(6),397-404(1985).
2. Lesage, D., Virelizier, H., Jankowski, C.K., et al. Identification of minor products obtained during radiolysis of tributylphosphate (TBP) Spectroscopy 13(4),275-290(1997).
