Methyltetrazine-PEG8-PFP ester is an PFP containing click chemistry reagent consisting of a methyltetrazine group. NHS ester is reactivewith primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slightly basic pH to form covalent bonds. Thus, this reagent can be used for modification of amine-containing molecules in organic media and the low mass weight will add minimal spacer to modified molecules. Methyltetrazine is reaactive with TCO via click chemistry.
