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BISPHENOL A DIGLYCIDYL ETHER RESIN
BISPHENOL A DIGLYCIDYL ETHER RESIN Chemical Properties
- Melting point:40-44 °C
- Boiling point:210 °C / 1mmHg
- Density 1,17 g/cm3
- refractive index 1.5735
- storage temp. Inert atmosphere,2-8°C
- form viscous liquid
- Water Solubility Soluble in 100% ethanol, dimethyl sulfoxide (100 mM), dimethyl formamide, chloroform, methanol, and ethanol (50 mM). Insoluble in water.
- BRN 299026
- CAS DataBase Reference1675-54-3(CAS DataBase Reference)
- IARC3 (Vol. 47, 71) 1999
- EPA Substance Registry SystemBisphenol A diglycidyl ether (1675-54-3)
BISPHENOL A DIGLYCIDYL ETHER RESIN Usage And Synthesis
- DescriptionMost epoxy resins result from polymerization of bisphenol A diglycidyl ether (BADGE). Delayed hypersensitivity is caused by the low-molecular-weight monomer BADGE (MW 340 g/mol), the dimer having a much lower sensitization power. This allergen caused contact dermatitis in six workers in a plant producing printed circuits boards made of copper sheets and fiberglass fabric impregnated with a brominated epoxy resin. It can also be contained in adhesives.
- Chemical PropertiesDiglycidyl ether of bisphenol A is a colorless to light amber liquid. Slight epoxy odor.
- UsesBisphenol A derivative. A PPARγ antagonist; exhibits estrogenic activity; An inhibitor of PPARγ and suppressor of TNFα.
- UsesIn the manufacture of epoxy resins and polycarbonates for food packaging.
- Production MethodsThe synthesis of the basic epoxy resin molecule involves the reaction of epichlorohydrin with bisphenol A, the latter requiring two basic intermediates for synthesis, acetone and phenol. Theoretically, the production of the bisphenol A diglycidyl ether requires 2 mol of epichlorohydrin for each mole of the phenol. Epoxy resins of higher molecular weight are obtained by reducing the epichlorohydrin/bisphenol A ratio. This reaction involves consumption of the initial epoxy groups in the epichlorohydrin and of some of the groups formed by dehydrohalogenation.
- General DescriptionOdorless yellowish brown liquid. Sinks in water.
- Air & Water ReactionsOxidizes readily in air to form unstable peroxides that may explode spontaneously [Bretherick 1979 p.151-154, 164]. Insoluble in water.
- Reactivity ProfileEpoxides, such as BISPHENOL A DIGLYCIDYL ETHER RESIN, are highly reactive. They polymerize in the presence of catalysts or when heated. These polymerization reactions can be violent. Compounds in this group react with acids, bases, and oxidizing and reducing agents. They react, possibly violently with water in the presence of acid and other catalysts.
- Health HazardContact with liquid irritates eyes. Prolonged or repeated contact with skin causes irritation and dermatitis.
- Fire HazardBISPHENOL A DIGLYCIDYL ETHER RESIN is probably combustible.
- Biological ActivityPPAR γ pure antagonist with micromolar affinity in 3T3-L1 and 3T3-F442A preadipocyte cells; selective over PPAR δ and PPAR α . Antagonizes the ability of rosiglitazone to stimulate transcriptional activity of PPAR γ . Acts as a PPAR γ agonist in an ECV304 cell line. Also produces PPARg-independent apoptosis of tumor cells via several mechanisms. Active in vivo .
- Contact allergensMost epoxy resins result from polymerization of bisphenol A diglycidyl ether (BADGE). Delayed hypersensitivity is caused by the low-molecular-weight monomer BADGE (Molecular Weight 340 g/mol), the dimer having much a lower sensitization power. This allergen caused contact dermatitis in six workers in a plant producing printed circuits boards made of copper sheets and fiber glass fabric impregnated with a brominated epoxy resin. It can be contained in adhesives.
- Potential ExposureDiglycidyl ether of bisphenol A is used as a basic active ingredient of epoxy resins.
- CarcinogenicityIn summary, a number of carcinogenicity studies involving the topical application of pure BADGE as well as EPON Resin 828 and other commercial BADGE-based resins have been carried out in experimental animals.Viewing the studies as a whole, the weight of evidence does not show that BADGE or BADGE-based epoxy resins are carcinogenic.
- IncompatibilitiesEasily oxidized in air; presumed to form unstable and explosive peroxides in storage. Incompatible with strong acids; strong oxidizers.
- Waste DisposalDissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
- Bisphenol A Impurity 8 Bisphenol A Impurity 6-d8 Bisphenol A Impurity 9-d4 MFCD02018974 Bisphenol A Impurity 2-d8 Bisphenol A impurity 5 Bisphenol A Impurity 3-d8 Bisphenol A impurity 2 Bisphenol A Impurity 7 Bisphenol A Impurity 5-d8 Bisphenol A impurity 6 4-[1-(4-hydroxyphenyl)-1-methylethyl]benzene-1,2-diol Bisphenol A impurity 3 BISPHENOL F DIGLYCIDYL ETHER Bisphenol A Impurity 7-d4 Bisphenol A Impurity 8-d4 BISPHENOL A-(3-CHLORO-2-HYDROXYPROPYL)-& Bisphenol A Impurity 4-d8
BISPHENOL A DIGLYCIDYL ETHER RESINSupplierMore
- Company Name:J & K SCIENTIFIC LTD.
- Tel:400-666-7788 010-82848833-
- Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel:400-660-8290 21-61259100-
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:18930552037 821-50328103-801
- Company Name:Alfa Aesar
- Company Name:TCI (Shanghai) Development Co., Ltd.
- Tel:021-67121386 / 800-988-0390