UNC2541 (25 μM; pretreatment around the sciatic nerve half an hour in advance) significantly abolishes the analgesic effect of ozone in CCI mice[2].
| Animal Model: | Adult male SPF-grade ICR mice and C57BL/6 mice, weighing 20-22g and aged 6-8 weeks (anesthetized with sodium pentobarbital and sciatic nerve was ligatured by 4-0 chromic gut sutures to establish Chronic constriction injury (CCI) model)[2] |
| Dosage: | 25 μM |
| Administration: | Pretreatment around the sciatic nerve half an hour in advance. |
| Result: | Significantly abolished the analgesic effect of ozone in CCI mice. |
