Anti-JNK antibody, Mouse monoclonal has been used in immunoblotting and enzyme linked immunosorbent assay (ELISA).
Anti-JNK antibody, Mouse monoclonal, (mouse IgG2a isotype) is derived from the hybridoma 1C2 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a recombinant protein. JNK1 (c-Jun N-terminal kinase), also known as MAPK8 (mitogen-activated protein kinase 8) is a member of the MAP kinase family. This gene is mapped to human chromosome 10q11.
JNK1 is also involved in UV (ultra violet) radiation induced apoptosis, which is thought to be related to cytochrome C-mediated cell death pathway.