2-chloro-N-[[4-(dimethylamino)phenyl]methyl]-N-[3-phenyl-3-(4-propan-2-yloxyphenyl)propyl]acetamide

NPD926 is an inducer of cancel cell death. NPD926 sensitized cells to inhibitors of system x(c)?, a cystine-glutamate antiporter considered to be a potential therapeutic target in cancers including cancer stem cells. Induction of excessive levels of reactive oxygen species (ROS) by small-molecule compounds has been considered a potentially effective therapeutic strategy against cancer cells, which are often subjected to chronic oxidative stress.