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SHR1258
Product Name
SHR1258
CAS
1269662-73-8
MF
C32H31ClN6O3
MW
583.08
EINECS
MOL File
1269662-73-8.mol
Chemical Properties
Boiling point
775.5±60.0 °C(Predicted)
Density
1.35±0.1 g/cm3(Predicted)
storage temp.
Store at -20°C
solubility
DMSO : 0.172 mg/mL (0.29 mM)
pka
12.30±0.43(Predicted)
form
Solid
color
Light yellow to yellow
Usage And Synthesis
Uses
Pyrotinib, is a potent and selective EGFR/HER2 dual inhibitor.
Preparation Products And Raw materials
Raw materials
(2R)-1-Methyl-2-Pyrrolidinecarboxaldehyde
Phosphonic acid, P-[2-[[4-[[3-chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]amino]-2-oxoethyl]-, diethyl ester
6-amino-4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-7-ethoxyquinoline-3-carbonitrile
BOC-L-Prolinol
L-(+)-Prolinol
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