1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)

Product Name1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)
CAS474922-90-2
MF(C2H4O)nC43H80NO10P.H3N
MW0
EINECS
MOL File474922-90-2.mol

Chemical Properties

storage temp.	-20°C
form	Solid
color	White to off-white

Usage And Synthesis

Description

18:1 PEG PE, MW 550 is a PEG lipid used in small unilamellar vesicles such as liposomes with two 18-carbon chain tails with single alkene bonds in both tails to deliver anticancer and antimalarial agents.

Uses

18:1 PEG350 PE is suitable for use:

in the preparation of lipid bilayer membranes to estimate the diameter of the ion channel formed by the Bacillus anthracis protective antigen 63 (PA63)
to prepare Gd-C5F12-phospholipid nanobubbles
to form aqueous dispersions and to study metal cation induced cubic phase

Uses

18:1 PEG2000 PE or 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] has been used as a component of liposome stock solution for depositing lipid bilayers on the flowcell surface. It may be used in lipid bilayer preparation.

Uses

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-1000] (18:1 PEG1000 PE) is suitable for fluorescent PEG-grafted liposomes/fluorescent stealth liposomes or liposomes.

General Description

18:1 PEG550 PE is a polyethylene glycol (PEG) conjugated phospholipid. PEGylated phospholipids are amphiphilic polymers, The molecular weight and exact mass are averages based on the polydispersity of PEG.

Biochem/physiol Actions

18:1 PEG5000 PE, also referred as 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000] (PEG5k-DOPE) in combination with lipid modified dendrimer copolymer supports co-delivery of siRNA and drugs to tumors.