Propargyl-PEG8-amine

Propargyl-PEG8-amine is a heterobifunctional reagent consisting of a propargyl group and an amine group. The amine group can form amide bonds with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The propargyl group can form triazole linkage with azides in copper catalyzed Click Chemistry reactions.

Propargyl-peg8-amine is used as a reactant in the synthesis of synthetic antibody mimics targeting prostate cancer.