RalfinaMide Mesylate

Chemical Properties

Melting point	230-235°C
storage temp.	2-8°C
solubility	H2O: >15mg/mL
form	powder
color	white to beige
optical activity	[α]/D 10 to 15° (c=1 HOAc)
Water Solubility	H2O: >15mg/mL
InChI	1S/C17H19FN2O2.CH4O3S/c1-12(17(19)21)20-10-13-6-8-15(9-7-13)22-11-14-4-2-3-5-16(14)18;1-5(2,3)4/h2-9,12,20H,10-11H2,1H3,(H2,19,21);1H3,(H,2,3,4)/t12-;/m0./s1
InChIKey	CHQVNINIGBRKGZ-YDALLXLXSA-N
SMILES	CS(O)(=O)=O.C[C@H](NCc1ccc(OCc2ccccc2F)cc1)C(N)=O

Hazard Codes	T
Risk Statements	25
Safety Statements	45
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3
Storage Class	6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
Hazard Classifications	Acute Tox. 3 Oral

Animal Model:	81 adult male Sprague–Dawley male rats (260–460 g)^[1]
Dosage:	80 mg/kg (7 days preoperatively), 30 mg/kg, 60 mg/kg (postoperative)
Administration:	Oral gavage; twice daily; until postoperative day 42
Result:	Suppressed neuropathic pain.