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7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one
Product Name
7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one
CAS
193686-76-9
MF
C17H16ClNO3S
MW
349.83
EINECS
MOL File
193686-76-9.mol
Chemical Properties
Boiling point
536.5±60.0 °C(Predicted)
Density
1.36
pka
-4.58±0.20(Predicted)
Usage And Synthesis
Uses
7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one is used as a reactant in the asymetric preparation of an intermediate in the synthesis of both enantiomers of Tolvaptan (T536650).
7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one Supplier
CONIER CHEM AND PHARMA LIMITED
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Beijing Comparison Pharmaceutical Technology Co., Ltd
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Related Product Information
2-Methyl-4-nitrobenzoyl chloride
5-Dehydro Tolvaptan
Tolvaptan Impurity 4 (DM-4105)
Ethyl 7-Chloro-5-oxo-1-toxyl-2,3,4,5,-tetrahydro-1H-benzo[b]azepine-4-carboxylate
Tolvaptan Impurity 18
Tolvaptan Impurity 13
5-Chloro-2-[(4-ethoxy-4-oxobutyl)[(4-methylphenyl)sulfonyl]amino]benzoic acid methyl ester
Tolvaptan Impurity 21
Tolvaptan Impurity 3 (DM-4104)
Tolvaptan Impurity 30
7-Chloro-1,2,3,4-tetrahydro-1-(2-methyl-4-nitrobenzoyl)-5H-1-benzazepin-5-one
Tolvaptan Impurity 17
Tolvaptan impurity 2
Tolvaptan Impurity 20
Tolvaptan Impurity 15
Tolvaptan Impurity 11
Tolvaptan Impurity 26
1-(4-Amino-2-methylbenzoyl)-7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one
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![7-Chloro-1,2,3,4-tetrahydro-1-[(4-methylphenyl)sulfonyl]-5H-1-benzazepin-5-one Structure](/CAS2/GIF/193686-76-9.gif)