γ2 - MSH (41 - 58), amide

γ-2-MSH (41-58), amide is derived from γ-2-MSH. γ-2-MSH is a twelve amino acid peptide that is derived from the N-terminal fragment of proopiomelanocortin (POMC) and contains the His-Phe-Arg-Trp motif common to all melanocortin endogenous agonist ligands[1].

[1] Joseph CG, et al. γ-Melanocyte stimulation hormone (γ-MSH) truncation studies results in the cautionary note that γ-MSH is not selective for the mouse MC3R over the mouse MC5R. Peptides. 2010 Dec;31(12):2304-13. DOI:10.1016/j.peptides.2010.08.025