tert-Butyl (R)-2-[[[(4-Methylphenyl)sulfonyl]oxy]methyl]-1-pyrrolidinecarboxylate is an intermediate in the synthesis of (2S)-Ethylpyrrolidine Hydrochloride (E818080), which is used as a reagent in the synthesis of N,N''-substituted-1,3-diamino-2-hydroxypropanes for treating Alzheimer''s disease. Also used as a reagent in the synthesis of cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as JAK kinase inhibitors for treatment of autoimmune disease, cancer, inflammatory disease, and other diseases.
