Gly-Leu-Met-NH2

Gly-Leu-Met-NH2 is a C-terminal tripeptide of Substance P (Substance P (HY-P0201)). Substance P is a neuropeptide[1].

ChEBI: Gly-L-Leu-L-Met-NH2 is a tripeptide composed of glycine, L-leucine and L-methioninamide joined in sequence by peptide linkages. It is a C-terminal fragment of substance P. It is functionally related to a glycine, a L-leucine and a L-methioninamide. It is a conjugate base of a Gly-L-Leu-L-Met-NH2(1+).

[1] Sandrine Sagan, et al. Conformational analysis of the C-terminal Gly-Leu-Met-NH2 tripeptide of substance P bound to the NK-1 receptor. Chem Biol. 2005 May;12(5):555-65. DOI:10.1016/j.chembiol.2005.03.005