2-(4-Bromophenyl)-6-chloroquinoline-4-carboxylicacid

Aminoacyl tRNA synthetase-IN-4 (Compound 1l) is an inhibitor of Aminoacyl tRNA synthetase, with an IC50 of 0.026 μM for C.albicans prolyl-tRNA synthetase. Aminoacyl tRNA synthetase-IN-4 can be used for antifungal research[1].

[1] Yu XY, et al. A series of quinoline analogues as potent inhibitors of C. albicans prolyl tRNA synthetase. Bioorg Med Chem Lett. 2001 Feb 26;11(4):541-4. DOI:10.1016/s0960-894x(00)00697-1