Cholesterol-doxorubicin

Cholesterol-doxorubicin (Chol-DOX) is a prodrug form of the anticancer agent doxorubicin (DOX; Item No. 15007).1 Chol-DOX, when combined with tocopherol polyethylene glycol succinate/tocofersolan (TPGS; Item No. 34661) in nanoassemblies, reduces MCF-7 and MDA-MB-231 breast cancer cell viability.WARNING This product is not for human or veterinary use.

[1] FILIPE OLIM. Self-Assembly of Cholesterol-Doxorubicin and TPGS into Prodrug-Based Nanoparticles with Enhanced Cellular Uptake and Lysosome-Dependent Pathway in Breast Cancer Cells[J]. European Journal of Lipid Science and Technology, 2021, 123 5. DOI: 10.1002/ejlt.202000337